Melanotan Peptides

Melanocyte-stimulating Hormone

If you are looking to buy melanocyte-stimulating hormones for your research projects, we have a full range of products for you to choose from. Scroll down to see our full range of alpha-melanotropin research hormones.

What is Melanocyte-stimulating Hormone?

Melanocyte-stimulating hormone is produced by the skin, hypothalamus, and the pituitary gland. It is the collective name for MSH peptides and plays a key role in producing colored pigmentation in the skin. By inducing specialized skin cells known as melanocytes, it creates a pigment called melanin, which protects cells from DNA damage.

Melanotropin hormones or intermedins are a group of hormones separated into three categories:

  1. Alpha-Melanocyte Stimulating Hormone (a-MSH)
  2. β-melanocyte-stimulating hormone (β-MSH)
  3. γ-melanocyte-stimulating hormone (γ-MSH)

How it Works

Following the release from the pituitary, Alpha-melanocyte-stimulating hormone[i] circulates in the blood and attaches to MCRs on pigment-containing cells known as melanocytes. In humans, the process leads to skin darkening with sunlight exposure functioning as the incentive for MSH production and secretion.

MSH Effects

While Melanocyte-stimulating hormone, also known as Alpha-MSH, is mainly known for its effect on pigment cells[ii], it can also supress appetite by manipulating receptors in the brain. That’s why it’s known both as a tanning treatment and as a weight loss treatment.

It also possesses powerful anti-inflammatory effects which can influence aldosterone hormone release, and has an effect on sexual behavior.

Buy Melanocyte-stimulating Hormone

Would you like to purchase melanocyte peptide for your scientific research? It is important to choose a professional, reliable, and respected company from whom to order these hormone chemicals.

With researchers fascinated by how melanocytes function and their role in human health, as well as in treating discoloration on skin, it’s becoming a highly in-demand drug.

You can buy melanotan from Peptide Sciences, a leading supplier of melanocyte-stimulating hormone peptides. This supplier is highly respected among the scientific community for its high-quality, high-purity range of products.

Take a look through our alpha melanocyte peptides below.

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Signs of Melanocyte-stimulating Hormone Deficiency

A deficiency in melanocyte-stimulating hormone results in a loss of natural protection from UV rays and a lack of skin pigmentation. A sufficiency can also increase inflammation, pain, urination, thirst, and cause sleep issues. Research also shows that an MSH deficiency can also result in increased food intake, weight gain, and obesity.

Effects of High Levels of MSH

According to research, there is a direct link between high levels of melanocyte-stimulating hormone and increased melanin production. This is normally the result of prolonger sun exposure and skin tanning.

Those with high blood level of alpha-MSH hormone generally do not tan well or have skin pigmentation, while fair-skinned people produce less melanin due to their fluctuations in MSH hormone receptors. Thus, they do not respond to melanocyte-stimulating treatment.

Melanocytes Research 2020

Extensive research is being carried out on pigmentation disorders using melanocyte models. So far, the research looks impressive and demonstrates how effective melanocyte-stimulating peptides are for tanning the skin, promoting weight loss, and treating pigmentation disorders.

While it is not FDA approved yet, with further research, scientists hope it will be available to the public as a treatment for medical conditions.


[i] Dorr, Robert T., Ruskin Lines, Norman Levine, Christine Brooks, Li Xiang, Victor J. Hruby, and Mac E. Hadley. “Evaluation of Melanotan-II, a Superpotent Cyclic Melanotropic Peptide in a Pilot Phase-I Clinical Study.” Life Sciences 58, no. 20 (April 1996): 1777–1784. doi:10.1016/0024-3205(96)00160-9.

[ii] Dong, Liang et al. “Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism.” Cancer research vol. 70,9 (2010): 3547-56. doi:10.1158/0008-5472.CAN-09-4596

Melanocyte-stimulating Hormone Research Peptides Scientists